Register for the CYP1B1 test
Estrogen exposure is a know risk factor for breast and prostate cancer. Enzymes associated with detoxification help control the conversion of estrogen into potentially carcinogenic metabolites. CYP1B1 gene single nucleotide polymorphisms (SNPs) resulting in protein alterations have been suggested to impact the conversion of estrogen to carcinogenic metabolites. If you have a SNP on CYP1B1, you are more likely to produce these carcinogenic metabolites. Specific nutritional supplements can counteract this effect and can lower your risk for either breast or prostate cancer.
Reference:
Meta- and Pooled Analyses of the Cytochrome P-450 1B1 Val432Leu
Polymorphism and Breast Cancer: A HuGE–GSEC Review
Paracchini V, S Raimondi, IT Gram, D Kang, NA Kocabas, et al.
American Journal of Epidemiology 165:115-125 (2007)